What did the CES 2026 pilot study show?

The 2026 CES pilot is small-scale exploratory research conducted with KBSI and Gachon University College of Medicine over 6 weeks. Observed volumetric changes included +1.835% hippocampal and +1.798% cerebellar regions. These results are promising but preliminary and have not been peer-reviewed. Systematic MRI + AI studies are currently in progress, and a confirmatory RCT is planned for 2027.

Neurelux | Brain Wellness Device

Q: What makes Neurélux different from other tPBM devices?

Three key differentiators: ① 800nm + 1000nm Band Dual Wavelength — rarely used in combination in home devices. ② HS FRAME™ Patented Thermal Management — 1.75 K/W thermal resistance (37× lower than conventional 65 K/W) ensures wavelength stability and consistent output. ③ Fanless Silent Operation — natural convection heat dissipation. Zero noise, zero vibration.

Pilot fMRI Imaging

Brain Connectivity Measurements

Actual fMRI data from the 2026 exploratory pilot study conducted at KBSI / Gachon University. Images represent individual participant results — not population averages.

Whole-Brain Functional Connectivity Matrix Before and After tPBM — LJY

0.036 → 0.057 Mean Whole-Brain Connectivity

Whole-brain functional connectivity matrix (Pre → Post). Red = positive correlation, blue = negative. Participant LJY (dementia). Mean connectivity increased from 0.036 to 0.057 after a single tPBM session.

Temporal SNR Brain Heat Map Before and After tPBM — LJY, +46.4%

+46.4% Temporal SNR Improvement

Temporal SNR brain heat maps (Pre → Post). Brighter regions indicate stronger, more stable fMRI signal. Mean tSNR increased from 56.6 to 82.9 (+46.4%). Participant LJY (dementia).

6-Week Whole-Brain Functional Connectivity Matrix Before and After tPBM — KYS, +107.9%

+107.9% Mean Connectivity (6-Week)

6-week longitudinal fMRI connectivity matrix (Pre → Post). Mean connectivity increased from 0.063 to 0.131 — a 107.9% improvement. Participant KYS (MCI). Extended use demonstrated cumulative enhancement in cross-regional brain coordination.

Default Mode Network DMN Connectivity Analysis Before and After tPBM — LJY

−0.057 → −0.032 DMN Within-Network Connectivity

Default Mode Network (DMN) connectivity before and after session. The DMN governs memory and self-referential processing — disrupted in Alzheimer's disease. Post-session DMN connectivity improved toward less-negative coupling. Participant LJY (dementia).

Exploratory pilot data from KBSI / Gachon University (2026). N=3 (dementia, MCI, healthy control). Not peer-reviewed. Individual subject results — not population averages. Does not constitute medical claims or guarantee similar outcomes.

Daily Experience

Focus, Built Into Your Routine

Neurélux delivers dual-band near-infrared light in a silent, non-contact format designed to fit naturally into work, reading, and recovery routines.

Before and after Neurelux — tired executive vs. focused and alert with DNIR brain wellness device

Before the Session During the Session

Conceptual visualization for illustrative purposes only. The visible light beams and brain overlay artistically represent invisible near-infrared light delivery. This image does not depict an actual measured result or guarantee cognitive improvement. Individual experiences may vary.

Mechanism

How Transcranial PBM Works

Four steps from photon to brain wellness

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Photon Delivery

800nm Band & 1000nm Band near-infrared light penetrates the skull and reaches brain tissue through non-invasive transcranial delivery.

Skull Penetration

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Cellular Absorption

Cytochrome c oxidase (CCO) in neuronal mitochondria absorbs the near-infrared photons, initiating a photochemical cascade.

CCO Activation

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ATP Synthesis

Mitochondrial energy production (ATP synthesis) is supported, potentially enhancing cellular metabolism and neural function.

Mitochondrial Energy

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Brain Wellness

Ongoing research explores cognitive conditioning, neural connectivity, and long-term brain wellness outcomes.

Wellness Outcomes

DNIR — Dual Near-Infrared

800nm Band + 1000nm Band

HS FRAME™ proprietary DNIR technology — a dual near-infrared combination not widely adopted in home tPBM devices

800nm Band

Primary Cortical Targeting · 800nm Band

The 800nm band is the key absorption band for cytochrome c oxidase (CCO). Well-established in transcranial PBM research for cortical stimulation and neural activation.

Primary CCO absorption window
Cortical layer penetration
Extensively studied in tPBM research

1000nm Band

Deep Penetration Potential · 1000nm Band

The 1000nm band demonstrates deeper tissue penetration potential, targeting structures beyond the cortical surface. Exploratory research ongoing.

Deeper penetration depth potential
Complementary to 800nm band
Rarely adopted in home devices

DNIR = Dual Near-Infrared. 1000nm band research is exploratory. Final clinical efficacy is subject to further peer-reviewed studies.

Proprietary Technology · 16 Years R&D

HS FRAME™ All-in-One Optical Semiconductor

The core platform powering proprietary DNIR technology — stable, high-power dual near-infrared tPBM made possible

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HS FRAME™ Special DNIR Technology

HS FRAME™ integrates the 800nm band and 1000nm band within a single all-in-one optical semiconductor module — enabling true DNIR (Dual Near-Infrared) delivery without thermal degradation or wavelength drift. Conventional multi-component structures cannot sustain both bands simultaneously at high power. HS FRAME™ solves this with its patented direct-bonding architecture.

1.75 K/W

Thermal Resistance

37×

Lower vs. Conventional

10×

Faster Heat Dissipation

30%

Junction Temp Reduction

2×

Longer Lifespan

Conventional LED Structure

8-Step Complex Thermal Transfer Path

LED Chip (Heat Source) 🔴

Solder

PCB Substrate

Thermal Paste (TIM)

Aluminum Heat Sink

Thermal Bottleneck

High heat load

Delayed dissipation

65 K/W

High Thermal Resistance

Droop — output degradation from heat buildup
Wavelength shift — efficacy loss under thermal load
Bulky heatsink — added weight and complex structure

Conventional LED chip thermal path visualization

Conventional LED module — complex multi-layer stack

10× thermal performance improvement

HS FRAME™

Direct Thermal Path — All-in-One Structure

Chip + Circuit + Heat Sink — unified in one structure

LED Chip

Direct bonding — no intermediate layers

HS FRAME™ Integrated Optical Semiconductor Module

Smooth Thermal Flow

Heat dissipated across full surface area

1.75 K/W

Dramatically Lower Thermal Resistance

Fanless (Silent)

Stable Wavelength

Lightweight Design

2× Longer Lifespan

HS FRAME All-in-One integrated LED module

HS FRAME™ module — chip · circuit · heat sink unified

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7-Country Patent Portfolio Registered across KR · US · EU · JP · CN · and more

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16 Years of Dedicated R&D 110B KRW cumulative R&D investment since 2010

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Innovation Product Designation Korea Public Procurement Service certified

* Based on internal testing vs. conventional 65 K/W design. Junction temperature reduction and lifespan data derived from thermal simulation and internal lab testing. No Wavelength Droop confirmed under continuous operation.

Product Lineup

Neurélux Lineup

Two configurations for every brain wellness need

FLAGSHIP

Series 01

Neurélux DTS PRO

Whole-Brain Care · Premium

The flagship full-transcranial tPBM device. Engineered for comprehensive brain wellness — from prefrontal cortex to deep cerebellar structures. Adjustable arm for precise positioning.

Wavelength 800nm + 1000nm Band (DNIR)
Contact Non-contact
Noise Fanless · Silent
Use Home / Office
Optical System 45W High-Power
Coverage Full Transcranial

Brain Coverage 95%

Full Transcranial — Frontal · Temporal · Parietal · Occipital

Buy Now

Series 02

Neurélux DTS LITE

Focus Care · Prevention

A precision photobiomodulation desk device designed for daily brain wellness sessions. Compact form factor, silent operation — fits seamlessly into any home or office setup.

Wavelength 800nm + 1000nm Band (DNIR)
Contact Non-contact
Noise Fanless · Silent
Use Home / Office
Optical System 18W Power

Brain Coverage 55%

Frontal / Temporal Region

Coming Soon

COMING SOON

Series 03 · Wearable

Neurélux HERNOA

Everyday Headset · On-Demand Brain Care

An AI-adaptive DNIR brain-care headset that works as an everyday personal-audio headset — and switches into guided Focus, Relax, Sleep, or Brain Care modes powered by HS FRAME™.

Wavelength 800nm + 1000nm Band (DNIR)
Form Factor Over-ear headset
Modes Focus / Relax / Sleep / Brain Care

Learn More at HERNOA.com

* Neurélux DTS PRO — Available Now (Launched June 19, 2026). DTS LITE — Coming Soon.

Research Roadmap

Research Progress

From exploratory pilot to confirmatory clinical evidence

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Completed 2026.03

KBSI & Gachon Univ. Exploratory Pilot

6-week exploratory pilot study collaboratively measured with the Korea Basic Science Institute and Gachon University College of Medicine. Observed volumetric changes in hippocampal and cerebellar regions.

fMRI 6-Week Pilot Study CES 2026

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In Progress 2026

MRI · AI-Based Systematic Study

Collaboration with M-Tech Lab. MRI + AI-based brain analysis methodology. SCI(E) journal paper in preparation for peer-reviewed publication.

MRI + AI M-Tech Lab SCI(E) Paper

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Planned 2027

Confirmatory RCT Clinical Trial

Full-scale randomized controlled trial (RCT) planned for 2027. Target: regulatory approval pathway and peer-reviewed clinical evidence.

RCT Clinical Trial Regulatory Pathway

FAQ

Frequently Asked Questions

Key questions about Neurélux answered

How does Neurélux work?

800nm Band and 1000nm Band near-infrared light penetrates the skull and is absorbed by cytochrome c oxidase (CCO) in neuronal mitochondria. This photochemical reaction may support mitochondrial ATP synthesis and cellular energy metabolism. Neurélux is a non-contact, home-use brain wellness device — not a medical treatment.

Is it a medical device?

Neurélux DTS PRO is currently offered as a general wellness product and is not cleared or approved as a medical device. It is not intended to diagnose, treat, cure, mitigate, or prevent any disease. Clinical research is ongoing to evaluate its potential future medical applications, with confirmatory RCT trials planned for 2027.

What makes it different from other home tPBM devices?

Three key differentiators set Neurélux apart:

① 800nm + 1000nm Band Dual Wavelength — rarely used in combination in home devices. Most home tPBM devices use only a single wavelength.

② HS FRAME™ Patented Thermal Management — 1.75 K/W thermal resistance (37× lower than conventional 65 K/W) ensures wavelength stability and consistent output throughout each session.

③ Fanless Silent Operation — natural convection heat dissipation. Zero noise, zero vibration.

Is the fMRI pilot data reliable?

The 2026 exploratory pilot study, collaboratively measured with the Korea Basic Science Institute (KBSI) and Gachon University College of Medicine, is small-scale research and has not been peer-reviewed. The observed volumetric changes (+1.835% hippocampal, +1.798% cerebellar) are promising but preliminary. Systematic studies using MRI + AI analysis are currently in progress with M-Tech Lab, and a confirmatory RCT is planned for 2027. Final efficacy confirmation awaits further peer-reviewed clinical research.

When will Neurélux be available?

Neurélux DTS PRO is now available for purchase (Launched June 19, 2026). DTS LITE is coming soon. For clinical collaboration and distribution partnership inquiries, please contact us.

Exploratory Pilot fMRI Data — 6 Weeks